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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1352372 Species: Homo sapiens RGD Object: Gene Symbol: ALOX15 Name: arachidonate 15-lipoxygenase

Acc ID: CHEBI:15367 Term: all-trans-retinoic acid Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry. CasRN: 302-79-4 Chemical ID: MESH:D014212

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
affects expression	EXP		6480464	CTD	Tretinoin affects the expression of ALOX15 protein	PMID:15996861
multiple interactions	EXP		6480464	CTD	Tretinoin affects the reaction [IL4 protein results in increased expression of ALOX15 protein]	PMID:15996861