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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1320387 Species: Homo sapiens RGD Object: Gene Symbol: SERPINB8 Name: serpin peptidase inhibitor, clade B (ovalbumin), member 8

Acc ID: CHEBI:15367 Term: all-trans-retinoic acid Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry. CasRN: 302-79-4 Chemical ID: MESH:D014212

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases expression	EXP		6480464	CTD	Tretinoin metabolite results in decreased expression of SERPINB8 mRNA Tretinoin results in decreased expression of SERPINB8 mRNA	PMID:15982314
affects expression	EXP		6480464	CTD	Tretinoin affects the expression of SERPINB8 mRNA	PMID:15498508