GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tfap2a | affects localization | ISO | TFAP2A (Homo sapiens) | 6480464 | CTD | Tretinoin affects the localization of TFAP2A protein | PMID:17229153 | Tfap2a | increases expression | ISO | TFAP2A (Homo sapiens) | 6480464 | CTD | Tretinoin results in increased expression of TFAP2A mRNA | PMID:17138961 PMID:17318229 PMID:21934132 | Tfap2a | multiple interactions | ISO | TFAP2A (Homo sapiens) | 6480464 | CTD | Tretinoin inhibits the reaction [TFAP2A protein binds to DPYSL2 promoter]; Tretinoin promotes the reaction [[NPM1 protein binds to TFAP2A protein] which binds to NPM1 promoter]; Tretinoin promotes the reaction [NPM1 protein binds to TFAP2A protein] | PMID:17229153 PMID:17318229 | |
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