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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2729 Species: Rattus norvegicus RGD Object: Gene Symbol: Gpx1 Name: glutathione peroxidase 1

Acc ID: CHEBI:15365 Term: acetylsalicylic acid Definition: Benzoic acid carrying an acetoxy group at the 2-position. A non-steroidal anti-inflammatory drug with moA cyclooxygenase inhibitor activity. CasRN: 50-78-2 Chemical ID: MESH:D001241

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases expression	ISO	RGD:10681	6480464	CTD	Aspirin results in decreased expression of GPX1 mRNA	PMID:21353610