GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Rxra | multiple interactions | ISO | Rxra (Mus musculus) | 6480464 | CTD | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of RXRA gene; [Methionine deficiency co-treated with Choline deficiency co-treated with RXRA gene mutant form] results in decreased expression of ACOX1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with RXRA gene mutant form] results in decreased expression of ACOX1 protein; [Methionine deficiency co-treated with Choline deficiency co-treated with RXRA gene mutant form] results in decreased expression of CPT1A mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with RXRA gene mutant form] results in decreased expression of FABP1 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with RXRA gene mutant form] results in decreased expression of FABP1 protein; [Methionine deficiency co-treated with Choline deficiency co-treated with RXRA gene mutant form] results in increased expression of ACACA mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with RXRA gene mutant form] results in increased expression of ACTA2 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with RXRA gene mutant form] results in increased expression of CXCL2 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with RXRA gene mutant form] results in increased expression of FAS mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with RXRA gene mutant form] results in increased expression of IL1B mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with RXRA gene mutant form] results in increased expression of IL1B protein; [Methionine deficiency co-treated with Choline deficiency co-treated with RXRA gene mutant form] results in increased expression of SREBF2 mRNA; [Methionine deficiency co-treated with Choline deficiency co-treated with RXRA gene mutant form] results in increased expression of TNF mRNA; RXRA affects the reaction [[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of CYP8B1 mRNA]; RXRA affects the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCC4 mRNA]; RXRA gene mutant form inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased activity of CYP2E1 protein]; RXRA gene mutant form promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of HMGCR mRNA] | PMID:18952117 PMID:20938992 | | ||||||||||||||||||||||
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