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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2993
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lcat
Name: lecithin cholesterol acyltransferase
Acc ID: CHEBI:15354
Term: choline
Definition: A choline that is the parent compound of the cholines class, consisting of ethanolamine having three methyl substituents attached to the amino function.
Chemical ID: MESH:D002794
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lcatincreases expressionISOLcat (Mus musculus)6480464CTDCholine results in increased expression of LCAT mRNAPMID:25178843
Lcatmultiple interactionsISOLcat (Mus musculus)6480464CTD[Choline deficiency co-treated with Methionine deficiency] results in increased expression of LCAT mRNAPMID:25178843
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