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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2532
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Edn1
Name: endothelin 1
Acc ID: CHEBI:15354
Term: choline
Definition: A choline that is the parent compound of the cholines class, consisting of ethanolamine having three methyl substituents attached to the amino function.
Chemical ID: MESH:D002794
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Edn1increases expressionISOEdn1 (Mus musculus)6480464CTDCholine results in increased expression of EDN1 proteinPMID:27567547
Edn1multiple interactionsISOEdn1 (Mus musculus)6480464CTDUrsolic Acid inhibits the reaction [Choline results in increased expression of EDN1 protein]PMID:27567547
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