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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2369
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cnr1
Name: cannabinoid receptor 1
Acc ID: CHEBI:15343
Term: acetaldehyde
Definition: The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke.
Chemical ID: MESH:D000079
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cnr1multiple interactionsEXP 6480464CTDAcetaldehyde promotes the reaction [Dronabinol results in increased expression of CNR1 mRNA]; Acetaldehyde promotes the reaction [glyceryl 2-arachidonate results in increased expression of CNR1 mRNA]PMID:21863215
Cnr1increases expressionISOCNR1 (Homo sapiens)6480464CTDAcetaldehyde results in increased expression of CNR1 mRNAPMID:21863215
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