GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Esr1 | decreases expression | EXP | | 6480464 | CTD | enzacamene results in decreased expression of ESR1 mRNA | PMID:19150460 | Esr1 | multiple interactions | EXP | | 6480464 | CTD | [Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of ESR1 mRNA | PMID:34383603 | Esr1 | increases activity | ISO | ESR1 (Homo sapiens) | 6480464 | CTD | enzacamene results in increased activity of ESR1 protein | PMID:12765243 | Esr1 | multiple interactions | ISO | ESR1 (Homo sapiens) | 6480464 | CTD | enzacamene binds to and results in increased activity of ESR1 protein | PMID:16079615 PMID:24004914 | |
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