Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	2532
Species:	Rattus norvegicus
RGD Object:	Gene
Symbol:	Edn1
Name:	endothelin 1

Acc ID:	CHEBI:135810
Term:	atrasentan
Definition:	null
Chemical ID:	MESH:C098644

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Edn1	multiple interactions	EXP		6480464	CTD	atrasentan inhibits the reaction [EDN1 protein results in increased abundance of Reactive Oxygen Species]	PMID:22431579

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.