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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2069
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Agt
Name: angiotensinogen
Acc ID: CHEBI:135806
Term: benidipine
Definition: null
Chemical ID: MESH:C061004
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Agtmultiple interactionsISOAGT (Homo sapiens)6480464CTD[Valsartan co-treated with benidipine] inhibits the reaction [AGT protein results in increased abundance of Aldosterone]; benidipine inhibits the reaction [AGT protein results in increased abundance of Aldosterone]; benidipine inhibits the reaction [AGT protein results in increased expression of CYP11B1 mRNA]; benidipine inhibits the reaction [AGT protein results in increased uptake of Calcium]PMID:18331727
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