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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3317
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pgr
Name: progesterone receptor
Acc ID: CHEBI:135742
Term: ormeloxifene
Definition: null
Chemical ID: MESH:D002486
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pgrincreases expressionEXP 6480464CTDCentchroman results in increased expression of PGR protein; ormeloxifene results in increased expression of PGR mRNAPMID:15914137 PMID:19460436
Pgrmultiple interactionsEXP 6480464CTD[Centchroman co-treated with Estradiol] results in decreased expression of PGR protein; ormeloxifene inhibits the reaction [Estradiol results in increased expression of PGR mRNA]PMID:15914137 PMID:19460436
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