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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3227
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Odc1
Name: ornithine decarboxylase 1
Acc ID: CHEBI:132238
Term: iron(III) nitrilotriacetate
Definition: An iron chelate resulting from the combination of equimolar amounts of iron(3+) and nitrilotriacetate(3-).
Chemical ID: MESH:C020326
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Odc1increases activityEXP 6480464CTDferric nitrilotriacetate results in increased activity of ODC1 proteinPMID:15949125 PMID:9667754
Odc1multiple interactionsEXP 6480464CTD[ferric nitrilotriacetate results in increased abundance of Hydroxyl Radical] which results in increased activity of ODC1 protein; Active Hexose Correlated Compound inhibits the reaction [[ferric nitrilotriacetate results in increased abundance of Hydroxyl Radical] which results in increased activity of ODC1 protein]; Vitamin E inhibits the reaction [ferric nitrilotriacetate results in increased activity of ODC1 protein]PMID:14623030 PMID:15949125
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