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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708474 Species: Rattus norvegicus RGD Object: Gene Symbol: Ugt1a8 Name: UDP glycosyltransferase 1 family, polypeptide A8

Acc ID: CHEBI:1156 Term: 2-hydroxyestrone Definition: A 2-hydroxy steroid that has formula C18H22O3. CasRN: 362-06-1 Chemical ID: MESH:C024980

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases glucuronidation	ISO	RGD:1348090	6480464	CTD	UGT1A9 protein results in increased glucuronidation of 2-hydroxyestrone	PMID:15117964