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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3000
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lep
Name: leptin
Acc ID: CHEBI:10136
Term: gingerol
Definition: A beta-hydroxy ketone that is 5-hydroxydecan-3-one substituted by a 4-hydroxy-3-methoxyphenyl moiety at position 1; believed to inhibit adipogenesis. It is a constituent of fresh ginger.
Chemical ID: MESH:C007845
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lepmultiple interactionsISOLep (Mus musculus)6480464CTDgingerol inhibits the reaction [Dietary Fats results in increased expression of LEP mRNA]; gingerol inhibits the reaction [Dietary Fats results in increased expression of LEP protein]PMID:21851089
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