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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62391 Species: Rattus norvegicus RGD Object: Gene Symbol: Ddit3 Name: DNA-damage inducible transcript 3

Acc ID: CHEBI:10110 Term: zidovudine Definition: A pyrimidine 2',3'-dideoxyribonucleoside compound having a 3'-azido substituent and thymine as the nucleobase. CasRN: 30516-87-1 Chemical ID: MESH:D015215

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:69165	6480464	CTD	[Zidovudine co-treated with Lamivudine] results in increased expression of DDIT3 mRNA	PMID:15784690
increases expression	ISO	RGD:69165	6480464	CTD	Zidovudine results in increased expression of DDIT3 mRNA	PMID:15784690