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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70913
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcc5
Name: ATP binding cassette subfamily C member 5
Acc ID: CHEBI:10106
Term: zearalenone
Definition: A macrolide comprising a fourteen-membered lactone fused to 1,3-dihydroxybenzene; a potent estrogenic metabolite produced by some Giberella species.
Chemical ID: MESH:D015025
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcc5affects expressionEXP 6480464CTDZearalenone affects the expression of ABCC5 proteinPMID:23707492
Abcc5decreases expressionEXP 6480464CTDZearalenone results in decreased expression of ABCC5 mRNAPMID:29627501
Abcc5increases expressionEXP 6480464CTDZearalenone results in increased expression of ABCC5 mRNAPMID:23707492
Abcc5multiple interactionsEXP 6480464CTDfulvestrant inhibits the reaction [Zearalenone results in increased expression of ABCC5 mRNA]PMID:23707492
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