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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619930
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcb11
Name: ATP binding cassette subfamily B member 11
Acc ID: CHEBI:10100
Term: zafirlukast
Definition: A N-sulfonylcarboxamide that has formula C31H33N3O6S.
Chemical ID: MESH:C062735
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcb11decreases activityISOABCB11 (Homo sapiens)6480464CTDzafirlukast results in decreased activity of ABCB11 proteinPMID:23956101 PMID:28437613
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