• View As List
• View As Table

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708379 Species: Rattus norvegicus RGD Object: Gene Symbol: Cyp3a2 Name: cytochrome P450, family 3, subfamily a, polypeptide 2

Acc ID: CHEBI:100241 Term: ciprofloxacin Definition: Quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively. CasRN: 85721-33-1 Chemical ID: MESH:D002939

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases activity	ISO	RGD:1352962	6480464	CTD	Ciprofloxacin results in decreased activity of CYP3A4 protein	PMID:11145498