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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737111 Species: Homo sapiens RGD Object: Gene Symbol: EGR1 Name: early growth response 1

Acc ID: CHEBI:15368 Term: acrolein Definition: An enal that has formula C3H4O. CasRN: 107-02-8 Chemical ID: MESH:D000171

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases expression	EXP		6480464	CTD	Acrolein results in increased expression of EGR1 mRNA Acrolein results in increased expression of EGR1 protein	PMID:20015449
increases expression	ISO	RGD:10512	6480464	CTD	Acrolein results in increased expression of EGR1 mRNA	PMID:18515264