GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735582
Species: Mus musculus
RGD Object: Gene
Symbol: Plcb1
Name: phospholipase C, beta 1
Acc ID: CHEBI:43000
Term: guanosine 5'-[gamma-thio]triphosphate
Definition: A nucleoside triphosphate analogue that has formula C10H16N5O13P3S.
CasRN: 37589-80-3
Chemical ID: MESH:D016244
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:33446480464CTDCaffeine inhibits the reaction [[dihydroxyphenylethylene glycol co-treated with Guanosine 5'-O-(3-Thiotriphosphate)] results in increased activity of PLCB1 protein]

Caffeine inhibits the reaction [Guanosine 5'-O-(3-Thiotriphosphate) results in increased activity of PLCB1 protein]

Theophylline inhibits the reaction [[dihydroxyphenylethylene glycol co-treated with Guanosine 5'-O-(3-Thiotriphosphate)] results in increased activity of PLCB1 protein]

Theophylline inhibits the reaction [Guanosine 5'-O-(3-Thiotriphosphate) results in increased activity of PLCB1 protein]

PMID:15998294
increases activityISORGD:33446480464CTDGuanosine 5'-O-(3-Thiotriphosphate) results in increased activity of PLCB1 protein

PMID:15998294
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