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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735389 Species: Homo sapiens RGD Object: Gene Symbol: BBC3 Name: BCL2 binding component 3

Acc ID: CHEBI:28499 Term: kaempferol Definition: A flavonol that has formula C15H10O6. CasRN: 520-18-3 Chemical ID: MESH:C006552

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	EXP		6480464	CTD	Caffeine inhibits the reaction [kaempferol results in increased expression of BBC3 protein] kaempferol promotes the reaction [BBC3 protein binds to BCL2L1 protein] TP53 protein affects the reaction [kaempferol promotes the reaction [BBC3 protein binds to BCL2L1 protein]]	PMID:19028473
increases expression	EXP		6480464	CTD	kaempferol results in increased expression of BBC3 protein	PMID:19028473