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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733315 Species: Mus musculus RGD Object: Gene Symbol: Il2 Name: interleukin 2

Acc ID: CHEBI:50692 Term: mifepristone Definition: A 3-oxo steroid that has formula C29H35NO2. CasRN: 84371-65-3 Chemical ID: MESH:D015735

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:730858	6480464	CTD	Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [CD28 protein results in increased secretion of IL2 protein]] Mifepristone inhibits the reaction [rimexolone inhibits the reaction [CD28 protein results in increased secretion of IL2 protein]]	PMID:20363256
multiple interactions	EXP		6480464	CTD	Mifepristone inhibits the reaction [Ethanol results in decreased expression of IL2 mRNA]	PMID:7473187