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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733189 Species: Mus musculus RGD Object: Gene Symbol: Taldo1 Name: transaldolase 1

Acc ID: CHEBI:46195 Term: paracetamol Definition: A derivative of phenol which has an acetamido substituent located para to the phenolic -OH group. CasRN: 103-90-2 Chemical ID: MESH:D000082

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	EXP		6480464	CTD	[Clofibrate co-treated with Acetaminophen] affects the expression of TALDO1 mRNA PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of TALDO1 mRNA]	PMID:17585979
multiple interactions	EXP		6480464	CTD	anthra(1,9-cd)pyrazol-6(2H)-one affects the reaction [TALDO1 gene mutant form promotes the reaction [Acetaminophen results in increased activity of and results in increased phosphorylation of MAPK8 protein]]	PMID:19436114
increases expression	ISO	RGD:620674	6480464	CTD	Acetaminophen results in increased expression of TALDO1 mRNA	PMID:15084756