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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732955 Species: Mus musculus RGD Object: Gene Symbol: Dusp1 Name: dual specificity phosphatase 1

Acc ID: CHEBI:46195 Term: paracetamol Definition: A derivative of phenol which has an acetamido substituent located para to the phenolic -OH group. CasRN: 103-90-2 Chemical ID: MESH:D000082

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	EXP		6480464	CTD	[Clofibrate co-treated with Acetaminophen] affects the expression of DUSP1 mRNA PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of DUSP1 mRNA]	PMID:17585979
increases expression	EXP		6480464	CTD	Acetaminophen results in increased expression of DUSP1 mRNA	PMID:20363829 PMID:11264010 PMID:18544908
increases expression	EXP		6480464	CTD	Acetaminophen results in increased expression of DUSP1 mRNA	PMID:11264010 PMID:20363829 PMID:18544908
affects expression	EXP		6480464	CTD	Acetaminophen affects the expression of DUSP1 mRNA	PMID:17562736 PMID:15606129
increases expression	EXP		6480464	CTD	Acetaminophen results in increased expression of DUSP1 mRNA	PMID:20363829 PMID:18544908 PMID:11264010
increases expression	ISO	RGD:620897	6480464	CTD	Acetaminophen results in increased expression of DUSP1 mRNA	PMID:17202762
increases expression	EXP		6480464	CTD	Acetaminophen results in increased expression of DUSP1 mRNA	PMID:18544908 PMID:11264010 PMID:20363829
increases expression	EXP		6480464	CTD	Acetaminophen results in increased expression of DUSP1 mRNA	PMID:18544908 PMID:20363829 PMID:11264010
increases expression	EXP		6480464	CTD	Acetaminophen results in increased expression of DUSP1 mRNA	PMID:11264010 PMID:18544908 PMID:20363829
affects expression	EXP		6480464	CTD	Acetaminophen affects the expression of DUSP1 mRNA	PMID:15606129 PMID:17562736
increases expression	ISO	RGD:732954	6480464	CTD	Acetaminophen results in increased expression of DUSP1 mRNA	PMID:21420995