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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730973 Species: Mus musculus RGD Object: Gene Symbol: Srebf2 Name: sterol regulatory element binding factor 2

Acc ID: CHEBI:3750 Term: clofibrate Definition: A propanoate ester that has formula C12H15ClO3. CasRN: 637-07-0 Chemical ID: MESH:D002994

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases expression	ISO	RGD:1307751	6480464	CTD	Clofibrate results in decreased expression of SREBF2 mRNA Clofibrate results in decreased expression of SREBF2 protein	PMID:17126302