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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730886 Species: Homo sapiens RGD Object: Gene Symbol: CREB1 Name: cAMP responsive element binding protein 1

Acc ID: CHEBI:4659 Term: disulfiram Definition: An organic disulfide that has formula C10H20N2S4. CasRN: 97-77-8 Chemical ID: MESH:D004221

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	EXP		6480464	CTD	Copper promotes the reaction [Disulfiram results in decreased activity of CREB1 protein] [Disulfiram co-treated with Copper] results in decreased activity of CREB1 protein	PMID:15367699