GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Plin2 | decreases expression | EXP | | 6480464 | CTD | Oxygen results in decreased expression of PLIN2 mRNA; Oxygen results in decreased expression of PLIN2 protein | PMID:16617452 | Plin2 | multiple interactions | EXP | | 6480464 | CTD | 2-chloro-5-nitrobenzanilide inhibits the reaction [rosiglitazone inhibits the reaction [Oxygen results in decreased expression of PLIN2 mRNA]]; 2-chloro-5-nitrobenzanilide inhibits the reaction [rosiglitazone inhibits the reaction [Oxygen results in decreased expression of PLIN2 protein]]; rosiglitazone inhibits the reaction [Oxygen results in decreased expression of PLIN2 mRNA]; rosiglitazone inhibits the reaction [Oxygen results in decreased expression of PLIN2 protein] | PMID:16617452 | Plin2 | decreases expression | ISO | Plin2 (Mus musculus) | 6480464 | CTD | Oxygen deficiency results in decreased expression of PLIN2 mRNA | PMID:21531777 | Plin2 | increases expression | ISO | PLIN2 (Homo sapiens) | 6480464 | CTD | Oxygen deficiency results in increased expression of PLIN2 mRNA; Oxygen deficiency results in increased expression of PLIN2 protein | PMID:24403227 PMID:34648812 | Plin2 | multiple interactions | ISO | PLIN2 (Homo sapiens) | 6480464 | CTD | 1-cyclopropyl-4-(4-((5-methyl-3-(3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazol-5-yl)-1H-pyrazol-1-yl)methyl)pyridin-2-yl)piperazine inhibits the reaction [Oxygen deficiency results in increased expression of PLIN2 mRNA]; [FV-429 compound co-treated with Oxygen deficiency] affects the expression of PLIN2 protein; [FV-429 compound co-treated with Paclitaxel] inhibits the reaction [Oxygen deficiency results in increased expression of PLIN2 protein]; [Paclitaxel co-treated with FV-429 compound co-treated with Deferoxamine] promotes the reaction [Oxygen deficiency results in increased expression of PLIN2 protein]; [Paclitaxel co-treated with FV-429 compound] inhibits the reaction [Oxygen deficiency results in increased expression of PLIN2 mRNA]; [Paclitaxel co-treated with FV-429 compound] inhibits the reaction [Oxygen deficiency results in increased expression of PLIN2 protein]; Deferoxamine promotes the reaction [Oxygen deficiency results in increased expression of PLIN2 protein]; HIF1A protein affects the reaction [Oxygen deficiency results in increased expression of PLIN2 protein] | PMID:24403227 PMID:34648812 | Plin2 | multiple interactions | ISO | Plin2 (Mus musculus) | 6480464 | CTD | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of PLIN2 mRNA | PMID:30529165 | | ||||||||||||||||||||||
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