GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Clic6 | increases expression | EXP | | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased expression of CLIC6 mRNA | PMID:32109520 | Clic6 | decreases expression | ISO | Clic6 (Mus musculus) | 6480464 | CTD | Tetrachlorodibenzodioxin results in decreased expression of CLIC6 mRNA | PMID:33956508 | Clic6 | decreases methylation | ISO | Clic6 (Mus musculus) | 6480464 | CTD | Tetrachlorodibenzodioxin results in decreased methylation of CLIC6 gene | PMID:21212295 | Clic6 | multiple interactions | ISO | Clic6 (Mus musculus) | 6480464 | CTD | [Tetrachlorodibenzodioxin co-treated with Lipopolysaccharides] results in decreased methylation of CLIC6 gene; Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CLIC6 promoter] | PMID:19654925 PMID:21212295 | | ||||||||||||||||||||||
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