GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Rela | multiple interactions | EXP | | 152995414 | RGD | sulfasalazine inhibits the reaction [2,4,6-trinitrobenzenesulfonic acid increases abundance of Nf-Kb protein] in rat colon | | Rela | affects localization | EXP | | 6480464 | CTD | Sulfasalazine affects the localization of RELA protein | PMID:16626516 | Rela | decreases localization | EXP | | 6480464 | CTD | Sulfasalazine results in decreased localization of RELA protein | PMID:17259377 | Rela | multiple interactions | EXP | | 6480464 | CTD | Sulfasalazine inhibits the reaction [Acetic Acid results in increased phosphorylation of RELA protein]; Sulfasalazine inhibits the reaction [Gentamicins results in increased expression of RELA protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of RELA protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of RELA protein] | PMID:16925772 PMID:21070844 PMID:35290143 PMID:35595039 | Rela | decreases activity | ISO | RELA (Homo sapiens) | 6480464 | CTD | Sulfasalazine results in decreased activity of RELA protein | PMID:15564333 | Rela | increases localization | ISO | RELA (Homo sapiens) | 6480464 | CTD | Sulfasalazine results in increased localization of RELA protein | PMID:15269287 | Rela | multiple interactions | ISO | RELA (Homo sapiens) | 6480464 | CTD | Sulfasalazine inhibits the reaction [Lipopolysaccharides results in increased activity of RELA protein]; Sulfasalazine inhibits the reaction [rasagiline results in increased localization of and results in increased activity of RELA protein]; Sulfasalazine inhibits the reaction [RELA protein promotes the reaction [Lipopolysaccharides results in increased expression of DIO2 mRNA]]; Sulfasalazine inhibits the reaction [TNF protein results in increased activity of RELA protein]; Sulfasalazine inhibits the reaction [TNF protein results in increased localization of and results in increased activity of RELA protein]; Sulfasalazine results in decreased expression of and results in decreased activity of RELA protein; Sulfasalazine results in decreased phosphorylation of and results in decreased activity of RELA protein | PMID:12135912 PMID:14687604 PMID:15955209 PMID:16728495 PMID:18089796 PMID:9486988 | Rela | multiple interactions | ISO | Rela (Mus musculus) | 6480464 | CTD | Sulfasalazine inhibits the reaction [Acetic Acid results in increased expression of RELA protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased expression of RELA protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased phosphorylation of RELA protein]; Sulfasalazine inhibits the reaction [RELA protein binds to ICAM1 promoter]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of RELA protein] | PMID:19956958 PMID:20823682 PMID:26102009 PMID:30972795 PMID:32272095 | |
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