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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 727889
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rela
Name: RELA proto-oncogene, NF-kB subunit
Acc ID: CHEBI:8062
Term: phenethyl caffeate
Definition: An alkyl caffeate ester in which 2-phenylethyl is the alkyl component.
Chemical ID: MESH:C055494
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Relamultiple interactionsISORELA (Homo sapiens)6480464CTDcaffeic acid phenethyl ester inhibits the reaction [Paclitaxel results in increased activity of RELA protein]; caffeic acid phenethyl ester inhibits the reaction [TNF protein results in increased activity of RELA protein]; caffeic acid phenethyl ester results in decreased activity of [NFKB1 protein binds to RELA protein]PMID:15291876 PMID:16052512 PMID:26562779
Relamultiple interactionsISORela (Mus musculus)6480464CTDcaffeic acid phenethyl ester inhibits the reaction [Zymosan results in increased activity of [NFKB1 protein binds to RELA protein]]PMID:11259437
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