GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Rela | increases expression | EXP | | 6480464 | CTD | Methamphetamine results in increased expression of RELA protein | PMID:30450033 | Rela | increases phosphorylation | EXP | | 6480464 | CTD | Methamphetamine results in increased phosphorylation of RELA protein | PMID:36914120 | Rela | multiple interactions | EXP | | 6480464 | CTD | GATA4 protein affects the reaction [Methamphetamine results in increased phosphorylation of RELA protein]; Lactulose inhibits the reaction [Methamphetamine results in increased expression of RELA protein] | PMID:30450033 PMID:36914120 | Rela | affects localization | ISO | RELA (Homo sapiens) | 6480464 | CTD | Methamphetamine affects the localization of RELA protein | PMID:26283214 | Rela | affects response to substance | ISO | Rela (Mus musculus) | 6480464 | CTD | RELA mRNA affects the susceptibility to Methamphetamine | PMID:19689456 | Rela | increases activity | ISO | Rela (Mus musculus) | 6480464 | CTD | Methamphetamine results in increased activity of RELA protein | PMID:34082047 | Rela | increases expression | ISO | Rela (Mus musculus) | 6480464 | CTD | Methamphetamine results in increased expression of RELA mRNA; Methamphetamine results in increased expression of RELA protein | PMID:35390362 PMID:35688268 | Rela | increases phosphorylation | ISO | Rela (Mus musculus) | 6480464 | CTD | Methamphetamine results in increased phosphorylation of RELA protein | PMID:32768653 PMID:32916201 | Rela | multiple interactions | ISO | RELA (Homo sapiens) | 6480464 | CTD | luzindole inhibits the reaction [Melatonin inhibits the reaction [Methamphetamine affects the localization of RELA protein]]; Melatonin inhibits the reaction [Methamphetamine affects the localization of RELA protein]; RELA protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; RELA protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; RELA protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; RELA protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein] | PMID:26283214 PMID:27323860 | Rela | multiple interactions | ISO | Rela (Mus musculus) | 6480464 | CTD | [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of RELA mRNA]; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of RELA protein]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased phosphorylation of RELA protein]; GPX1 protein affects the reaction [Methamphetamine results in increased activity of RELA protein]; L 365260 inhibits the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased phosphorylation of RELA protein]]; Methamphetamine results in increased expression of and results in increased phosphorylation of RELA protein; obeticholic acid inhibits the reaction [Methamphetamine results in increased expression of and results in increased phosphorylation of RELA protein]; obeticholic acid inhibits the reaction [Methamphetamine results in increased expression of RELA protein]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of RELA mRNA]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of RELA protein] | PMID:32916201 PMID:34082047 PMID:35390362 PMID:35688268 PMID:36720452 | | ||||||||||||||||||||||
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