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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 727889
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rela
Name: RELA proto-oncogene, NF-kB subunit
Acc ID: CHEBI:4948
Term: Evodiamine
Definition: A beta-carboline that has formula C19H17N3O.
Chemical ID: MESH:C049639
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Relamultiple interactionsISORELA (Homo sapiens)6480464CTDevodiamine inhibits the reaction [Hydrogen Peroxide results in increased activity of RELA protein]; evodiamine inhibits the reaction [IL1B protein results in increased activity of RELA protein]; evodiamine inhibits the reaction [Okadaic Acid results in increased activity of RELA protein]; evodiamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; evodiamine inhibits the reaction [TNF protein affects the localization of RELA protein]; evodiamine inhibits the reaction [TNF protein results in increased acetylation of RELA protein]; evodiamine inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]; evodiamine inhibits the reaction [TNF protein results in increased activity of RELA protein]PMID:15710601
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