GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Rela | increases activity | EXP | | 6480464 | CTD | Cyclophosphamide results in increased activity of RELA protein | PMID:25451569 | Rela | increases expression | EXP | | 6480464 | CTD | Cyclophosphamide results in increased expression of RELA mRNA; Cyclophosphamide results in increased expression of RELA protein; Cyclophosphamide results in increased expression of RELA protein modified form | PMID:19303104 PMID:20433640 PMID:37419146 | Rela | increases phosphorylation | EXP | | 6480464 | CTD | Cyclophosphamide results in increased phosphorylation of RELA protein | PMID:32197949 | Rela | multiple interactions | EXP | | 6480464 | CTD | Anthocyanins inhibits the reaction [Cyclophosphamide results in increased activity of RELA protein]; Melatonin inhibits the reaction [Cyclophosphamide results in increased expression of RELA protein]; parthenolide inhibits the reaction [Cyclophosphamide results in increased expression of RELA protein modified form]; Plant Extracts inhibits the reaction [Cyclophosphamide results in increased activity of RELA protein]; Quercetin inhibits the reaction [Cyclophosphamide results in increased expression of RELA mRNA]; sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Cyclophosphamide results in increased phosphorylation of RELA protein]; Valsartan inhibits the reaction [Cyclophosphamide results in increased phosphorylation of RELA protein] | PMID:19303104 PMID:20433640 PMID:25451569 PMID:32197949 PMID:37419146 | Rela | increases phosphorylation | ISO | Rela (Mus musculus) | 6480464 | CTD | Cyclophosphamide results in increased phosphorylation of RELA protein | PMID:30506662 | Rela | multiple interactions | ISO | Rela (Mus musculus) | 6480464 | CTD | Cyclophosphamide results in increased localization of and results in increased activity of RELA protein; Dexamethasone inhibits the reaction [Cyclophosphamide results in increased localization of and results in increased activity of RELA protein]; ganoderic acid A inhibits the reaction [Cyclophosphamide results in increased phosphorylation of RELA protein] | PMID:22099998 PMID:30506662 | |
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