GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Rela | affects localization | EXP | | 6480464 | CTD | cobaltous chloride affects the localization of RELA protein | PMID:21925238 | Rela | increases expression | EXP | | 6480464 | CTD | cobaltous chloride results in increased expression of RELA protein | PMID:21499890 | Rela | multiple interactions | EXP | | 6480464 | CTD | cobaltous chloride inhibits the reaction [Oxygen deficiency results in increased expression of RELA protein]; cobaltous chloride inhibits the reaction [Oxygen deficiency results in increased localization of and results in increased activity of RELA protein]; Protein Kinase Inhibitors inhibits the reaction [cobaltous chloride affects the localization of RELA protein]; rhodioloside inhibits the reaction [cobaltous chloride results in increased expression of RELA protein] | PMID:18635243 PMID:21296072 PMID:21499890 PMID:21925238 | Rela | affects localization | ISO | Rela (Mus musculus) | 6480464 | CTD | cobaltous chloride affects the localization of RELA protein | PMID:23684559 | Rela | increases expression | ISO | RELA (Homo sapiens) | 6480464 | CTD | cobaltous chloride results in increased expression of RELA protein; cobaltous chloride results in increased expression of RELA protein modified form | PMID:20974702 PMID:29966676 | Rela | increases phosphorylation | ISO | RELA (Homo sapiens) | 6480464 | CTD | cobaltous chloride results in increased phosphorylation of RELA protein | PMID:21533553 PMID:25815440 | Rela | multiple interactions | ISO | RELA (Homo sapiens) | 6480464 | CTD | Acetylcysteine inhibits the reaction [cobaltous chloride results in increased phosphorylation of RELA protein]; cobaltous chloride inhibits the reaction [Cyclosporine results in increased phosphorylation of RELA protein]; cobaltous chloride promotes the reaction [rhein affects the localization of RELA protein]; RELA protein promotes the reaction [cobaltous chloride results in increased expression of PTGS2 protein]; RELA protein promotes the reaction [cobaltous chloride results in increased secretion of CXCL8 protein]; RELA protein promotes the reaction [cobaltous chloride results in increased secretion of IL6 protein]; Resveratrol inhibits the reaction [cobaltous chloride results in increased phosphorylation of RELA protein] | PMID:21457705 PMID:21533553 PMID:22343435 PMID:25815440 | Rela | multiple interactions | ISO | Rela (Mus musculus) | 6480464 | CTD | 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Phloretin inhibits the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5] results in increased phosphorylation of RELA protein]]; [cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5] results in increased phosphorylation of RELA protein; Phloretin inhibits the reaction [[cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5] results in increased phosphorylation of RELA protein] | PMID:32408695 | | ||||||||||||||||||||||
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