GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Rela | decreases response to substance | EXP | | 6480464 | CTD | RELA protein results in decreased susceptibility to Cadmium Chloride | PMID:16478757 | Rela | increases phosphorylation | EXP | | 6480464 | CTD | Cadmium Chloride results in increased phosphorylation of RELA protein | PMID:35122928 | Rela | multiple interactions | EXP | | 6480464 | CTD | [Cadmium Chloride results in increased abundance of Cadmium] which affects the localization of RELA protein; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of RELA protein; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of RELA protein; [SN50 peptide co-treated with Cadmium Chloride] results in decreased activity of RELA protein; agomelatine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of RELA protein]; Butylated Hydroxytoluene inhibits the reaction [Cadmium Chloride results in decreased activity of RELA protein]; Cadmium Chloride affects the reaction [COL2A1 protein results in increased expression of RELA protein]; Cadmium Chloride results in decreased phosphorylation of and results in decreased activity of RELA protein; galangin inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which affects the localization of RELA protein]; U 78517F inhibits the reaction [Cadmium Chloride results in decreased activity of RELA protein] | PMID:16478757 PMID:26070417 PMID:34510229 PMID:35384154 PMID:36356678 | Rela | affects localization | ISO | RELA (Homo sapiens) | 6480464 | CTD | Cadmium Chloride affects the localization of RELA protein | PMID:17391980 PMID:22041583 PMID:22961094 | Rela | affects localization | ISO | Rela (Mus musculus) | 6480464 | CTD | Cadmium Chloride affects the localization of RELA protein | PMID:15240131 PMID:23948867 | Rela | decreases phosphorylation | ISO | Rela (Mus musculus) | 6480464 | CTD | Cadmium Chloride results in decreased phosphorylation of RELA protein | PMID:28666365 | Rela | increases expression | ISO | Rela (Mus musculus) | 6480464 | CTD | Cadmium Chloride results in increased expression of RELA protein | PMID:21420465 | Rela | increases phosphorylation | ISO | RELA (Homo sapiens) | 6480464 | CTD | Cadmium Chloride results in increased phosphorylation of RELA protein | PMID:27634459 PMID:28288823 PMID:35122928 | Rela | increases phosphorylation | ISO | Rela (Mus musculus) | 6480464 | CTD | Cadmium Chloride results in increased phosphorylation of RELA protein | PMID:35983679 | Rela | multiple interactions | ISO | RELA (Homo sapiens) | 6480464 | CTD | [Cadmium Chloride affects the activity of GLRX protein] inhibits the reaction [cinnamaldehyde results in increased glutathionylation of RELA protein]; [Cadmium Chloride results in increased abundance of Cadmium] which affects the localization of RELA protein; [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of RELA mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of RELA protein; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RELA protein]; KT 5823 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RELA protein]; MitoTEMPO inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which affects the localization of RELA protein]; PPARG protein inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which affects the localization of RELA protein]; tin protoporphyrin IX inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RELA protein] | PMID:20351055 PMID:32917723 PMID:34510229 PMID:35122928 PMID:35301059 | Rela | multiple interactions | ISO | Rela (Mus musculus) | 6480464 | CTD | [Cadmium Chloride results in increased abundance of Cadmium] which affects the localization of RELA protein; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of RELA protein; arjunolic acid inhibits the reaction [Cadmium Chloride results in increased expression of RELA protein]; fargesin inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RELA protein]; Polystyrenes inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of RELA protein] | PMID:21420465 PMID:32917723 PMID:35983679 PMID:37022104 | | ||||||||||||||||||||||
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