GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Rela | increases activity | EXP | | 6480464 | CTD | Cocaine results in increased activity of RELA protein | PMID:19183502 | Rela | multiple interactions | EXP | | 6480464 | CTD | SCH 23390 inhibits the reaction [Cocaine results in increased activity of RELA protein] | PMID:19183502 | Rela | increases localization | ISO | Rela (Mus musculus) | 6480464 | CTD | Cocaine results in increased localization of RELA protein | PMID:20354174 | Rela | multiple interactions | ISO | Rela (Mus musculus) | 6480464 | CTD | acetovanillone inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of RELA protein]; AG 1879 inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of RELA protein]; Cocaine promotes the reaction [RELA protein binds to CCL2 promoter]; Cocaine results in increased activity of and affects the localization of RELA protein; Cocaine results in increased phosphorylation of and results in increased activity of RELA protein; GPX1 protein inhibits the reaction [Cocaine affects the localization of RELA protein]; GPX1 protein inhibits the reaction [Cocaine results in increased activity of and affects the localization of RELA protein]; N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of RELA protein]; RELA mutant form inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; SIGMAR1 mutant form inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of RELA protein] | PMID:20354174 PMID:31059705 | |
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