GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Per1 | increases expression | EXP | | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased expression of PER1 mRNA | PMID:23871856 PMID:33387578 | Per1 | affects expression | ISO | Per1 (Mus musculus) | 6480464 | CTD | Tetrachlorodibenzodioxin affects the expression of PER1 mRNA | PMID:21570461 PMID:24680724 PMID:26377647 | Per1 | decreases expression | ISO | Per1 (Mus musculus) | 6480464 | CTD | Tetrachlorodibenzodioxin results in decreased expression of PER1 mRNA; Tetrachlorodibenzodioxin results in decreased expression of PER1 protein | PMID:16556773 PMID:20106950 | Per1 | multiple interactions | ISO | Per1 (Mus musculus) | 6480464 | CTD | [Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in increased expression of PER1 mRNA; [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of PER1 mRNA; PER1 affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; PER1 protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; PER1 protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] | PMID:19038280 PMID:20371273 PMID:25975270 PMID:28433925 | |
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