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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 71101
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcc3
Name: ATP binding cassette subfamily C member 3
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcc3multiple interactionsEXP 6480464CTD[resveratrol co-treated with Streptozocin] results in increased expression of ABCC3 mRNA; resveratrol inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC3 mRNA]; resveratrol inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC3 protein]PMID:25418378 PMID:25905778
Abcc3increases expressionISOABCC3 (Homo sapiens)6480464CTDResveratrol results in increased expression of ABCC3 mRNA; Resveratrol results in increased expression of ABCC3 proteinPMID:18634814
Abcc3multiple interactionsISOABCC3 (Homo sapiens)6480464CTDresveratrol metabolite promotes the reaction [ABCC3 protein results in increased transport of estradiol-17 beta-glucuronide]PMID:19114588
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