GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Gsk3b | multiple interactions | EXP | | 6480464 | CTD | wortmannin inhibits the reaction [chaetoglobosins results in increased phosphorylation of GSK3B protein]; wortmannin inhibits the reaction [GRK2 protein results in increased phosphorylation of GSK3B protein]; wortmannin inhibits the reaction [rosiglitazone results in increased phosphorylation of GSK3B protein] | PMID:18040759 PMID:19566839 PMID:28759639 | Gsk3b | decreases expression | ISO | Gsk3b (Mus musculus) | 6480464 | CTD | wortmannin results in decreased expression of GSK3B protein modified form | PMID:15842767 | Gsk3b | decreases phosphorylation | ISO | GSK3B (Homo sapiens) | 6480464 | CTD | wortmannin results in decreased phosphorylation of GSK3B protein | PMID:20090934 PMID:23178381 | Gsk3b | multiple interactions | ISO | GSK3B (Homo sapiens) | 6480464 | CTD | Wortmannin affects the reaction [sphingosine 1-phosphate affects the reaction [beta-N-methylamino-L-alanine results in increased expression of GSK3B protein]]; Wortmannin inhibits the reaction [Bortezomib results in decreased activity of and results in increased phosphorylation of GSK3B protein]; Wortmannin inhibits the reaction [Estradiol results in increased phosphorylation of GSK3B protein]; Wortmannin inhibits the reaction [Liraglutide inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of GSK3B protein]]; Wortmannin inhibits the reaction [sodium arsenite results in increased phosphorylation of and results in increased activity of GSK3B protein]; Wortmannin inhibits the reaction [Zinc results in increased phosphorylation of GSK3B protein] | PMID:12614848 PMID:16076840 PMID:17513037 PMID:24085292 PMID:25769802 PMID:31173752 | Gsk3b | multiple interactions | ISO | Gsk3b (Mus musculus) | 6480464 | CTD | Melatonin inhibits the reaction [wortmannin results in decreased expression of GSK3B protein modified form]; Vitamin E inhibits the reaction [wortmannin results in decreased expression of GSK3B protein modified form]; wortmannin inhibits the reaction [notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in decreased expression of GSK3B protein modified form]] | PMID:15842767 PMID:23170834 | | ||||||||||||||||||||||
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