GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Gsk3b | increases expression | ISO | GSK3B (Homo sapiens) | 6480464 | CTD | gingerol results in increased expression of GSK3B protein | PMID:27645308 | Gsk3b | increases phosphorylation | ISO | Gsk3b (Mus musculus) | 6480464 | CTD | gingerol results in increased phosphorylation of GSK3B protein | PMID:26498061 | Gsk3b | increases response to substance | ISO | Gsk3b (Mus musculus) | 6480464 | CTD | GSK3B protein results in increased susceptibility to gingerol | PMID:26498061 | Gsk3b | multiple interactions | ISO | GSK3B (Homo sapiens) | 6480464 | CTD | gingerol inhibits the reaction [IL1B protein results in increased expression of GSK3B protein]; gingerol inhibits the reaction [IL1B protein results in increased phosphorylation of GSK3B protein]; GSK3B protein affects the reaction [gingerol results in increased expression of GDF15 protein] | PMID:18058799 PMID:27645308 | Gsk3b | multiple interactions | ISO | Gsk3b (Mus musculus) | 6480464 | CTD | GSK3B protein promotes the reaction [gingerol results in decreased expression of CEBPA mRNA]; GSK3B protein promotes the reaction [gingerol results in decreased expression of CEBPA protein]; GSK3B protein promotes the reaction [gingerol results in decreased expression of PPARG mRNA]; GSK3B protein promotes the reaction [gingerol results in decreased expression of PPARG protein] | PMID:26498061 | |
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