GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp6 | multiple interactions | EXP | | 6480464 | CTD | CASP6 protein affects the reaction [resveratrol results in decreased expression of SLC9A1 protein]; CAT protein inhibits the reaction [resveratrol results in increased cleavage of and results in increased activity of CASP6 protein]; Phenanthrolines inhibits the reaction [resveratrol results in increased cleavage of and results in increased activity of CASP6 protein]; resveratrol results in increased expression of and results in increased cleavage of and results in increased activity of CASP6 protein | PMID:18951995 | Casp6 | decreases activity | ISO | Casp6 (Mus musculus) | 6480464 | CTD | resveratrol results in decreased activity of CASP6 protein | PMID:20940732 | Casp6 | increases activity | ISO | CASP6 (Homo sapiens) | 6480464 | CTD | resveratrol results in increased activity of CASP6 protein | PMID:18497562 | Casp6 | increases activity | ISO | Casp6 (Mus musculus) | 6480464 | CTD | Resveratrol results in increased activity of CASP6 protein | PMID:37482209 | Casp6 | multiple interactions | ISO | CASP6 (Homo sapiens) | 6480464 | CTD | [Plant Extracts co-treated with Resveratrol] results in increased expression of CASP6 mRNA; [Resveratrol co-treated with TNFSF10 protein] results in increased activity of CASP6 protein; BAX protein promotes the reaction [Resveratrol promotes the reaction [CASP6 protein results in increased cleavage of LMNA protein]]; Resveratrol affects the reaction [Fluorouracil results in increased activity of CASP6 protein]; Resveratrol promotes the reaction [CASP6 protein results in increased cleavage of LMNA protein]; Resveratrol results in increased cleavage of and results in increased activity of CASP6 protein; TP53 affects the reaction [Resveratrol affects the reaction [Fluorouracil results in increased activity of CASP6 protein]]; TP53 affects the reaction [Resveratrol results in increased activity of CASP6 protein]; TP53 protein promotes the reaction [Resveratrol promotes the reaction [CASP6 protein results in increased cleavage of LMNA protein]] | PMID:15763656 PMID:16518869 PMID:18497562 PMID:23557933 | Casp6 | multiple interactions | ISO | Casp6 (Mus musculus) | 6480464 | CTD | benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone promotes the reaction [resveratrol results in decreased activity of CASP6 protein]; CASP6 protein affects the reaction [resveratrol results in decreased expression of SLC9A1 mRNA]; CASP6 protein affects the reaction [resveratrol results in decreased expression of SLC9A1 protein]; resveratrol promotes the reaction [benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone results in decreased activity of CASP6 protein] | PMID:18951995 PMID:20940732 | | ||||||||||||||||||||||
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