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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70500
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mapk1
Name: mitogen activated protein kinase 1
Acc ID: CHEBI:16412
Term: lipopolysaccharide
Definition: Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).
Chemical ID: MESH:D008070
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk1increases activityEXP 6480464CTDLipopolysaccharides results in increased activity of MAPK1 proteinPMID:10469353 PMID:10857765 PMID:12608646 PMID:21415432
Mapk1increases expressionEXP 6480464CTDLipopolysaccharides results in increased expression of MAPK1PMID:18197913
Mapk1increases phosphorylationEXP 6480464CTDLipopolysaccharides results in increased phosphorylation of MAPK1 proteinPMID:16683234 PMID:16934299 PMID:17172471 PMID:18047562 PMID:21308383 PMID:21717513 PMID:25557508 PMID:27098997 PMID:27302421 PMID:30980805 PMID:31707400
Mapk1multiple interactionsEXP 6480464CTD2-(1-carboxy-2-(3-(3,5-dichlorobenzyl)-3H-imidazol-4-yl)ethylamino)-4-methylpentanoic acid inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; 7-Ala-angiotensin (1-7) inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; [Lead co-treated with Lipopolysaccharides] results in increased phosphorylation of MAPK1 protein; [Lipopolysaccharides co-treated with IFNG protein] results in increased phosphorylation of MAPK1 protein; [Lipopolysaccharides co-treated with IFNG] results in increased phosphorylation of MAPK1 protein; ADRB2 protein promotes the reaction [Terbutaline inhibits the reaction [Lipopolysaccharides results in increased activity of MAPK1 protein]]; Albuterol inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK1 protein]; alisol B 23-acetate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; Apigenin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; Curcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; Cysteine analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; ICI 118551 inhibits the reaction [Terbutaline inhibits the reaction [Lipopolysaccharides results in increased activity of MAPK1 protein]]; Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK1 protein; Manganese promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased phosphorylation of MAPK1 protein]; MAPK1 protein promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; Plant Extracts inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; Simvastatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; Sodium Salicylate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Terbutaline inhibits the reaction [Lipopolysaccharides results in increased activity of MAPK1 protein]; triptolide inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]PMID:10357911 PMID:10469353 PMID:10857765 PMID:12608646 PMID:16044092 PMID:16488514 PMID:16683234 PMID:16934299 PMID:18047562 PMID:20519841 PMID:21308383 PMID:21717513 PMID:21943492 PMID:25557508 PMID:27098997 PMID:27302421 PMID:31707400
Mapk1increases activityISOMapk1 (Mus musculus)6480464CTDLipopolysaccharides results in increased activity of MAPK1 proteinPMID:14530214 PMID:21204955
Mapk1increases expressionISOMAPK1 (Homo sapiens)6480464CTDLipopolysaccharides results in increased expression of MAPK1 protein modified formPMID:18209571
Mapk1increases expressionISOMapk1 (Mus musculus)6480464CTDLipopolysaccharides results in increased expression of MAPK1 mRNA; Lipopolysaccharides results in increased expression of MAPK1 protein; Lipopolysaccharides results in increased expression of MAPK1 protein modified formPMID:15832817 PMID:18205790 PMID:19135555 PMID:23182953 PMID:23246826 PMID:23268108 PMID:23348408 PMID:35833596 PMID:36807594
Mapk1increases phosphorylationISOMAPK1 (Homo sapiens)6480464CTDLipopolysaccharides results in increased phosphorylation of MAPK1 proteinPMID:16890772 PMID:18625914 PMID:19010997 PMID:20307528 PMID:21147091 PMID:21877189 PMID:21956143 PMID:22124178 PMID:22226621 PMID:24967690 PMID:26335192 PMID:26862037 PMID:27129696 PMID:29217270 PMID:29925859 PMID:30794626 PMID:37182445
Mapk1increases phosphorylationISOMapk1 (Mus musculus)6480464CTDLipopolysaccharides results in increased phosphorylation of MAPK1 proteinPMID:11023991 PMID:11123339 PMID:11163183 PMID:11543732 PMID:12848851 PMID:14644621 PMID:14734799 PMID:15778123 PMID:15795323 PMID:15933225 PMID:16023107 PMID:16373689 PMID:16724238 PMID:17698059 PMID:18683823 PMID:19051357 PMID:19293636 PMID:19376148 PMID:19540866 PMID:1970628 PMID:20381601 PMID:20712904 PMID:20923188 PMID:21048310 PMID:21125213 PMID:21232528 PMID:21316417 PMID:21396905 PMID:21528358 PMID:21544733 PMID:21548916 PMID:21575647 PMID:21831303 PMID:21963823 PMID:21988173 PMID:22060784 PMID:22080918 PMID:22102286 PMID:22102721 PMID:22155221 PMID:22155741 PMID:22180763 PMID:22227475 PMID:22363816 PMID:22687552 PMID:22952890 PMID:22974838 PMID:23256447 PMID:23735482 PMID:24561310 PMID:25342887 PMID:25451575 PMID:25451593 PMID:25780039 PMID:25818598 PMID:26055553 PMID:26505893 PMID:26620692 PMID:26686910 PMID:27523796 PMID:27568862 PMID:27569861 PMID:27718290 PMID:27751938 PMID:28512713 PMID:29113806 PMID:29470957 PMID:29673161 PMID:29906494 PMID:31350693 PMID:31654708 PMID:31707400 PMID:32800949 PMID:33285210 PMID:33617879 PMID:35616142 PMID:35833596 PMID:37182445 PMID:37390879 PMID:37477137
Mapk1multiple interactionsISOMAPK1 (Homo sapiens)6480464CTD1,6-hexamethylene diisocyanate promotes the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; 2,3-bis(3'-hydroxybenzyl)butyrolactone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; 7-Ala-angiotensin (1-7) inhibits the reaction [diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]]; [Lipopolysaccharides results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK1 protein; ACE2 protein affects the reaction [diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]]; acetovanillone inhibits the reaction [[Lipopolysaccharides results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK1 protein]; acetovanillone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [[Lipopolysaccharides results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK1 protein]; arctigenin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; ARHGEF2 mutant form inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; CBR1 protein modified form inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; CRT 0066101 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; diphenyleneiodonium inhibits the reaction [[Lipopolysaccharides results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK1 protein]; eupafolin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; Fluorescein-5-isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; Genistein inhibits the reaction [Lipopolysaccharides affects the localization of and results in increased phosphorylation of MAPK1 protein]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]]; glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; herbimycin inhibits the reaction [Lipopolysaccharides affects the localization of and results in increased phosphorylation of MAPK1 protein]; honokiol inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; Lipopolysaccharides affects the localization of and results in increased phosphorylation of MAPK1 protein; Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK1 protein; Particulate Matter analog affects the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; PGGT1B inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; phillygenin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; Plant Extracts inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; Quercetin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; Resveratrol inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; RHOA mutant form inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; Simvastatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; Telmisartan inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; Vehicle Emissions analog affects the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; Y 27632 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]PMID:10653605 PMID:15671028 PMID:16890772 PMID:18625914 PMID:20307528 PMID:21147091 PMID:21391979 PMID:21877189 PMID:22124178 PMID:22226621 PMID:24967690 PMID:25818598 PMID:26335192 PMID:26862037 PMID:27129696 PMID:29217270 PMID:29740324 PMID:37182445
Mapk1multiple interactionsISOMapk1 (Mus musculus)6480464CTD17-hydroxyjolkinolide B inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Lipopolysaccharides results in increased expression of MAPK1 protein modified form]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; 2-(3-benzoyl)-4-hydroxy-1,1-dioxo-2H-1,2-benzothiazine-2-yl-1-phenylethanone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; 2-chloro-4'-methoxychalcone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; 4-methylbenzaldehyde analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; [[PTPN6 protein results in increased phosphorylation of MAPK1 protein] which results in increased activity of CEBPB protein] promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased expression of MAPK1 mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased phosphorylation of MAPK1 protein]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased expression of MAPK1 mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]]; [Curcumin binds to 4-bis(2-chloroethyl)aminobenzaldehyde] inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; [Drugs, Chinese Herbal co-treated with niuhuang] promotes the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; [Galactosamine co-treated with Lipopolysaccharides] results in increased expression of MAPK1 protein modified form; [Lead co-treated with Lipopolysaccharides] results in increased phosphorylation of MAPK1 protein; [Lipopolysaccharides co-treated with Galactosamine] results in increased expression of MAPK1 protein modified form; [Lipopolysaccharides co-treated with IFNG protein] results in increased phosphorylation of MAPK1 protein; [Lipopolysaccharides co-treated with IFNG] results in increased phosphorylation of MAPK1 protein; [Sirolimus results in decreased activity of MTOR protein] inhibits the reaction [Resveratrol inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]]; AG 127 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; alisol B 23-acetate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; apigenin-6,8-di-C-glycopyranoside inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; arctigenin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; arctiin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; baicalein inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of MAPK1 protein modified form]; Bee Venoms inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; beta-ionone inhibits the reaction [Lipopolysaccharides results in increased expression of MAPK1 protein modified form]; Caffeine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; Capsaicin inhibits the reaction [Lipopolysaccharides results in increased activity of MAPK1 protein]; capsazepine inhibits the reaction [Lipopolysaccharides results in increased activity of MAPK1 protein]; Carbenoxolone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; CD14 protein affects the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; chaetoglobosins inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; Chalcone analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; coagulin-L inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; cordycepin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; CRT 0066101 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; Cryptoxanthins inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; cudratricusxanthone A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; cynatratoside-C inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; Dexamethasone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; Drugs, Chinese Herbal inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Drugs, Chinese Herbal inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; EIF2AK2 protein affects the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; ethyl pyruvate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; Folic Acid inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; fructose-1,6-diphosphate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; fucoxanthin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; gentiopicroside inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased expression of MAPK1 protein modified form]; Ginkgo biloba extract inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; goniothalamin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; GSTP1 protein inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; GW 506033X inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; hinokiflavone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; isoeugenol inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; ITGAM protein affects the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; juzentaihoto inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; kaempferol 7-O-glucoside inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; kaempferol inhibits the reaction [Lipopolysaccharides results in increased expression of MAPK1 protein modified form]; Ketamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; Lentinan inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; licochalcone B analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; Lipopolysaccharides inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK1 protein]; Lipopolysaccharides promotes the reaction [Polystyrenes results in increased expression of MAPK1 mRNA]; Lipopolysaccharides promotes the reaction [Polystyrenes results in increased phosphorylation of MAPK1 protein]; Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK1 protein; lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; Lithium promotes the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Luteolin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; MAP3K8 protein affects the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; MAPK1 protein promotes the reaction [Lipopolysaccharides inhibits the reaction [TGFB1 protein results in increased expression of SMAD6 mRNA]]; matairesinol inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; Melitten inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK1 protein]; methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; MK615 extract inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; Niclosamide inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; patchouli alcohol inhibits the reaction [Lipopolysaccharides results in increased expression of MAPK1 protein modified form]; phlorofucofuroeckol A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; Plant Extracts inhibits the reaction [Lipopolysaccharides results in increased expression of MAPK1 protein modified form]; Polystyrenes promotes the reaction [Lipopolysaccharides results in increased expression of MAPK1 mRNA]; Polystyrenes promotes the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; protocatechuic acid inhibits the reaction [Lipopolysaccharides results in increased expression of MAPK1 protein]; Pyrazines inhibits the reaction [Lipopolysaccharides results in increased expression of MAPK1 protein modified form]; Quercetin inhibits the reaction [Lipopolysaccharides results in increased expression of MAPK1 protein modified form]; Quercetin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Quercetin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; resiniferatoxin inhibits the reaction [Lipopolysaccharides results in increased activity of MAPK1 protein]; Resveratrol inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; scolymoside inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; shogaol inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; Silymarin inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of MAPK1 protein modified form]; soyasaponin Ab inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; trametinib inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; VAV1 protein affects the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; vitisin A inhibits the reaction [Lipopolysaccharides results in increased expression of MAPK1 protein modified form]; wogonin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased phosphorylation of MAPK1 protein]; Wortmannin inhibits the reaction [Resveratrol inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]]; Xanthones inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; zinc protoporphyrin inhibits the reaction [2-(3-benzoyl)-4-hydroxy-1,1-dioxo-2H-1,2-benzothiazine-2-yl-1-phenylethanone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]]; zinc protoporphyrin promotes the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]PMID:11123339 PMID:11163183 PMID:11529938 PMID:11543732 PMID:12619901 PMID:12848851 PMID:14530214 PMID:15778123 PMID:15832817 PMID:15933225 PMID:16009389 PMID:16023107 PMID:16373689 PMID:16581537 PMID:16880258 PMID:17570326 PMID:17698059 PMID:17996413 PMID:18683823 PMID:19051357 PMID:19135555 PMID:19159680 PMID:19376148 PMID:19540866 PMID:1970628 PMID:20558151 PMID:20850421 PMID:21048310 PMID:21232528 PMID:21295571 PMID:21316417 PMID:21422245 PMID:21528358 PMID:21831303 PMID:21943492 PMID:21963823 PMID:21988173 PMID:22060784 PMID:22080918 PMID:22102286 PMID:22155221 PMID:22227475 PMID:22342441 PMID:22363816 PMID:22952890 PMID:22974838 PMID:23106696 PMID:23246826 PMID:23256447 PMID:23268108 PMID:23348408 PMID:23362215 PMID:23831309 PMID:24561310 PMID:24626144 PMID:25342887 PMID:25451593 PMID:25780039 PMID:26686910 PMID:27523796 PMID:27568862 PMID:27569861 PMID:27718290 PMID:28512713 PMID:29113806 PMID:29470957 PMID:29673161 PMID:31350693 PMID:31707400 PMID:33285210 PMID:33617879 PMID:35616142 PMID:35833596 PMID:36807594 PMID:37182445 PMID:37390879 PMID:37477137
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