GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mapk1 | increases phosphorylation | EXP | | 6480464 | CTD | Tretinoin results in increased phosphorylation of MAPK1 protein | PMID:19635392 | Mapk1 | multiple interactions | EXP | | 6480464 | CTD | [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one co-treated with Tretinoin] results in decreased phosphorylation of MAPK1 protein; [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with Tretinoin] results in decreased phosphorylation of MAPK1 protein; [Hydrogen Peroxide co-treated with Tretinoin] results in increased phosphorylation of MAPK1 protein; [Quercetin co-treated with Tretinoin] results in decreased phosphorylation of MAPK1 protein; CAMK2B protein promotes the reaction [Tretinoin results in increased phosphorylation of MAPK1 protein]; Quercetin inhibits the reaction [[Hydrogen Peroxide co-treated with Tretinoin] results in increased phosphorylation of MAPK1 protein]; Tretinoin results in decreased phosphorylation of and results in decreased activity of MAPK1 protein | PMID:16043492 PMID:19635392 PMID:25203460 | Mapk1 | affects phosphorylation | ISO | MAPK1 (Homo sapiens) | 6480464 | CTD | Tretinoin affects the phosphorylation of MAPK1 protein | PMID:21487212 | Mapk1 | decreases phosphorylation | ISO | MAPK1 (Homo sapiens) | 6480464 | CTD | Tretinoin results in decreased phosphorylation of MAPK1 protein | PMID:20576349 PMID:31934280 | Mapk1 | increases phosphorylation | ISO | MAPK1 (Homo sapiens) | 6480464 | CTD | Tretinoin results in increased phosphorylation of MAPK1 protein | PMID:16052510 PMID:16329108 PMID:16470170 PMID:17293044 PMID:19038232 | Mapk1 | increases phosphorylation | ISO | Mapk1 (Mus musculus) | 6480464 | CTD | Tretinoin results in increased phosphorylation of MAPK1 protein | PMID:17026715 | Mapk1 | multiple interactions | ISO | MAPK1 (Homo sapiens) | 6480464 | CTD | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tretinoin results in increased phosphorylation of MAPK1 protein]; [LCP2 protein co-treated with CSF1R protein] promotes the reaction [Tretinoin results in increased phosphorylation of MAPK1 protein]; [Tretinoin co-treated with Genistein] results in increased phosphorylation of MAPK1 protein; [Tretinoin co-treated with Retinoids] results in increased phosphorylation of MAPK1 protein; ARL6IP5 protein affects the reaction [Tretinoin results in increased phosphorylation of MAPK1 protein]; arsenic trioxide promotes the reaction [Tretinoin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; geldanamycin inhibits the reaction [Tretinoin results in increased phosphorylation of MAPK1 protein]; Tretinoin promotes the reaction [CPG-oligonucleotide results in increased phosphorylation of MAPK1 protein]; Tretinoin results in increased phosphorylation of and affects the localization of and results in increased activity of MAPK1 protein; Tretinoin results in increased phosphorylation of and results in increased activity of MAPK1 protein; U 0126 inhibits the reaction [Tretinoin results in increased phosphorylation of MAPK1 protein] | PMID:15383624 PMID:16149052 PMID:16439309 PMID:16922813 PMID:17209053 PMID:17293044 PMID:20615082 | Mapk1 | multiple interactions | ISO | Mapk1 (Mus musculus) | 6480464 | CTD | U 0126 inhibits the reaction [Tretinoin results in increased phosphorylation of MAPK1 protein] | PMID:17026715 | |
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