GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mapk1 | decreases phosphorylation | EXP | | 6480464 | CTD | manganese chloride results in decreased phosphorylation of MAPK1 protein | PMID:25981801 | Mapk1 | increases phosphorylation | EXP | | 6480464 | CTD | manganese chloride results in increased phosphorylation of MAPK1 protein | PMID:15010209 PMID:15342272 PMID:16787641 PMID:23811825 PMID:24324973 PMID:30040983 | Mapk1 | multiple interactions | EXP | | 6480464 | CTD | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased phosphorylation of MAPK1 protein]; [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK1 protein; GW 506033X promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK1 protein]; manganese chloride results in increased phosphorylation of and results in increased activity of MAPK1 protein; pyrazolanthrone promotes the reaction [manganese chloride results in increased phosphorylation of MAPK1 protein]; Resveratrol inhibits the reaction [manganese chloride results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [manganese chloride results in increased phosphorylation of MAPK1 protein] | PMID:15342272 PMID:16787641 PMID:20937724 PMID:23811825 PMID:32574669 | Mapk1 | increases activity | ISO | MAPK1 (Homo sapiens) | 6480464 | CTD | manganese chloride results in increased activity of MAPK1 protein | PMID:20152896 | Mapk1 | increases phosphorylation | ISO | MAPK1 (Homo sapiens) | 6480464 | CTD | manganese chloride results in increased phosphorylation of MAPK1 protein | PMID:19084589 PMID:20152896 | Mapk1 | multiple interactions | ISO | MAPK1 (Homo sapiens) | 6480464 | CTD | NTF3 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of MAPK1 protein] | PMID:31676349 | Mapk1 | multiple interactions | ISO | Mapk1 (Mus musculus) | 6480464 | CTD | [manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of MAPK1 protein; [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK1 protein; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK1 protein] | PMID:31676349 PMID:31690173 | |
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