GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mapk1 | increases phosphorylation | EXP | | 6480464 | CTD | Acrolein results in increased phosphorylation of MAPK1 protein | PMID:12487375 PMID:20359552 | Mapk1 | multiple interactions | EXP | | 6480464 | CTD | [ferric oxide analog co-treated with Acrolein] results in increased phosphorylation of MAPK1 protein; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [Acrolein results in increased phosphorylation of MAPK1 protein]]; Simvastatin inhibits the reaction [Acrolein results in increased phosphorylation of MAPK1 protein] | PMID:20359552 PMID:24847785 | Mapk1 | increases phosphorylation | ISO | MAPK1 (Homo sapiens) | 6480464 | CTD | Acrolein results in increased phosphorylation of MAPK1 protein | PMID:11329622 PMID:11504702 PMID:15531749 PMID:18951912 PMID:29964147 | Mapk1 | increases phosphorylation | ISO | Mapk1 (Mus musculus) | 6480464 | CTD | Acrolein results in increased phosphorylation of MAPK1 protein | PMID:20153347 | Mapk1 | multiple interactions | ISO | MAPK1 (Homo sapiens) | 6480464 | CTD | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Acrolein results in increased phosphorylation of MAPK1 protein]; RTKI cpd inhibits the reaction [Acrolein results in increased phosphorylation of MAPK1 protein] | PMID:11329622 PMID:15531749 | Mapk1 | multiple interactions | ISO | Mapk1 (Mus musculus) | 6480464 | CTD | RTKI cpd inhibits the reaction [Acrolein results in increased phosphorylation of MAPK1 protein] | PMID:20153347 | |
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