GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nfkb1 | increases expression | ISO | NFKB1 (Homo sapiens) | 6480464 | CTD | Paraquat results in increased expression of NFKB1 mRNA | PMID:20883675 PMID:35641671 | Nfkb1 | multiple interactions | ISO | NFKB1 (Homo sapiens) | 6480464 | CTD | Paraquat promotes the reaction [RELA protein binds to NFKB1 promoter] | PMID:22043816 | Nfkb1 | multiple interactions | ISO | Nfkb1 (Mus musculus) | 6480464 | CTD | [Maneb co-treated with Paraquat] results in increased expression of NFKB1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of NFKB1 mRNA]; NFKB1 protein mutant form inhibits the reaction [Paraquat results in increased expression of CAT mRNA]; Paraquat affects the localization of [NFKB1 protein binds to RELA protein]; Paraquat promotes the reaction [endotoxin, Escherichia coli affects the localization of [NFKB1 protein binds to RELA protein]]; Paraquat promotes the reaction [NFKB1 protein binds to NFKB1 protein]; Paraquat promotes the reaction [NFKB1 protein binds to RELA protein]; Paraquat promotes the reaction [NFKB1 protein binds to RELB protein]; SB 203580 inhibits the reaction [Paraquat affects the localization of [NFKB1 protein binds to RELA protein]]; SB 203580 inhibits the reaction [Paraquat promotes the reaction [endotoxin, Escherichia coli affects the localization of [NFKB1 protein binds to RELA protein]]]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of NFKB1 mRNA] | PMID:11728812 PMID:16919916 PMID:23963992 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |