GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nfkb1 | increases activity | ISO | NFKB1 (Homo sapiens) | 6480464 | CTD | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of NFKB1 protein | PMID:18508827 | Nfkb1 | increases expression | ISO | NFKB1 (Homo sapiens) | 6480464 | CTD | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of NFKB1 mRNA | PMID:16582591 PMID:16835749 | Nfkb1 | multiple interactions | ISO | NFKB1 (Homo sapiens) | 6480464 | CTD | Bungarotoxins inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of NFKB1 mRNA]; Mecamylamine inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of NFKB1 mRNA]; SN50 peptide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of NFKB1 protein]; U 0126 inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of NFKB1 protein] | PMID:16835749 PMID:18508827 | |
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