GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mapk14 | increases expression | ISO | Mapk14 (Mus musculus) | 6480464 | CTD | 4-hydroxy-2-nonenal results in increased expression of MAPK14 mRNA | PMID:19191707 | Mapk14 | multiple interactions | ISO | MAPK14 (Homo sapiens) | 6480464 | CTD | 4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK14 protein; Acetylcysteine inhibits the reaction [[4-hydroxy-2-nonenal co-treated with Hydrogen Peroxide] results in increased activity of MAPK14 protein]; alpha-Tocopherol inhibits the reaction [[4-hydroxy-2-nonenal co-treated with Hydrogen Peroxide] results in increased activity of MAPK14 protein]; Hydrogen Peroxide promotes the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK14 protein] | PMID:12684028 | Mapk14 | multiple interactions | ISO | Mapk14 (Mus musculus) | 6480464 | CTD | 4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK14 protein; resveratrol inhibits the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK14 protein] | PMID:16322078 | | ||||||||||||||||||||||
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