GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cdk2 | multiple interactions | EXP | | 6480464 | CTD | AHR affects the reaction [Benzo(a)pyrene results in increased activity of [CCNA2 protein binds to CDK2 protein]]; Benzo(a)pyrene results in increased activity of [CCNA2 protein binds to CDK2 protein] | PMID:17141280 | Cdk2 | affects methylation | ISO | CDK2 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene affects the methylation of CDK2 3' UTR; Benzo(a)pyrene affects the methylation of CDK2 promoter | PMID:27901495 | Cdk2 | decreases expression | ISO | CDK2 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in decreased expression of CDK2 mRNA | PMID:21632981 PMID:21802500 | Cdk2 | decreases expression | ISO | Cdk2 (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in decreased expression of CDK2 mRNA; Benzo(a)pyrene results in decreased expression of CDK2 protein | PMID:35038060 | Cdk2 | increases expression | ISO | CDK2 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in increased expression of CDK2 mRNA | PMID:19027820 PMID:32234424 PMID:33411230 | Cdk2 | increases expression | ISO | Cdk2 (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in increased expression of CDK2 mRNA | PMID:22342234 | |
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